THE SCIENTIST- Optical Cell Sorting
Science AAAS Highlight
by RACHEL BERKOWITZ
… A new wave of label-free methods is offering researchers ways to identify subgroups of cells in live cultures and to home in on the most pertinent populations. Still, many label-free methods rely on only one cell characteristic or are hobbled by their low throughput. To overcome these limitations, researchers are devising tools that rapidly pump high volumes of cells through tiny microfluidic channels etched into a chip and combine the novel use of optics with new image-processing tools.
The Scientist explores how these label-free techniques are helping to rapidly and accurately identify and isolate subsets of cells from a larger population.
Full Article: Optical Cell Sorting, The Scientist, December 2017,
Novel biosensor technology could allow rapid detection of Ebola virus
by Mark I. Stockman
Measuring minute amounts of chemical and biological objects in the environment and in living organisms is one of the most common and important tasks in chemistry, biology, medicine, environmental monitoring, transportation, homeland security, and defense. Although the existing methods of sensing and detection are numerous and powerful, they are not without shortcomings: insufficient sensitivity; long detection times; necessity for enzymatic, fluorescent, or radioactive labeling; high costs, and so on. Optical spectroscopic methods have the advantage of being fast, noncontact, and relatively inexpensive, but they are not necessarily sensitive enough.
Full Article: Nanoplasmonic sensing and detection, Science, Vol. 348, pp. 287-288,
In 2010, Ahmet Ali Yanik published his first paper on the rapid detection of Ebola virus using new biosensor technology he and colleagues at Boston University had invented. But he found there was little interest at the time in developing the technology further.
"People told me that there wasn't any profit in it because this disease only affects people in the developing world," Yanik said.